Ozobax DS (Baclofen) for Multiple Sclerosis

Overview
Ozobax DS is approved by the U.S. Food and Drug Administration (FDA) to treat spasticity caused by multiple sclerosis (MS), especially to reduce flexor spasms, clonus (rhythmic muscle contractions), muscle rigidity, and associated pain. It is also sometimes used to manage spasticity in individuals with spinal cord injuries or diseases. Ozobax DS is also known by its drug name, baclofen.

Ozobax DS belongs to the class of drugs known as gamma-aminobutyric acid (GABA-ergic) agonists. It works by reducing the excessive activity of nerves in the spinal cord, helping to alleviate muscle spasms and stiffness associated with MS.

How do I take it?
Prescribing information states that Ozobax DS is taken orally as a liquid solution. Treatment generally begins with a low dose divided into several daily doses, gradually increasing as directed by a health care provider. It is important to follow the prescribed dosing schedule and not stop taking the medication abruptly, as this can lead to serious complications. Always take Ozobax DS exactly as prescribed by your health care provider.

Side effects
Common side effects of Ozobax DS include drowsiness, dizziness, and weakness.

Rare but serious side effects may include severe withdrawal symptoms if the drug is stopped abruptly (such as seizures or hallucinations), neonatal withdrawal symptoms in pregnant individuals who discontinue use near delivery, and worsening of certain conditions such as psychosis, schizophrenia, or epilepsy. Ozobax DS may also cause sedation and impaired coordination, and its effects may be heightened when combined with alcohol or other central nervous system depressants.

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Label: Ozobax DS — Baclofen Solution - DailyMed