List of Treatments for Multiple Sclerosis

Acthar Gel (Repository corticotropin hormone)

Overview
Acthar Gel is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat conditions including multiple sclerosis, psoriasis, rheumatoid arthritis, and lupus. Acthar Gel is also… read more

Adderall (Amphetamine/Dextroamphetamine)

Overview
Adderall is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat attention deficit disorder with hyperactivity. Adderall is sometimes prescribed off-label to treat fatigue… read more

Ampyra (Dalfampridine)

Overview
Ampyra is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to improve walking speed in adults with all types of multiple sclerosis (MS). It is the first drug that has been… read more

Aricept (Donepezil)

Overview
Aricept is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat mild, moderate, and severe Alzheimer’s disease. Aricept is sometimes prescribed off-label to treat cognitive… read more

Aubagio (Teriflunomide)

Overview
Aubagio is a prescription medication approved by the Food and Drug Administration (FDA) for treating adults with relapsing forms of multiple sclerosis (MS). It is also known by its drug name, Teriflunomide.… read more

Avonex (Interferon beta 1a)

Overview
Avonex is a prescription medication approved by the Food and Drug Administration (FDA) for adults who have had their first episode of multiple sclerosis (MS) symptoms and whose magnetic resonance imaging (MRI)… read more

Bafiertam (Monomethyl fumarate)

Overview
Bafiertam is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat adults with relapsing forms of multiple sclerosis, including clinically isolated syndrome, relapsing-remitting… read more

Betaseron (Interferon beta 1b)

Overview
Betaseron is a prescription medication approved by the Food and Drug Administration (FDA) for adults who have had their first episode of multiple sclerosis (MS) symptoms and whose magnetic resonance imaging… read more

Briumvi (Ublituximab-xiiy)

Overview
Briumvi is a prescription drug approved by the Food and Drug Administration (FDA) to treat adults with relapsing forms of multiple sclerosis (MS), including clinically isolated syndrome, relapsing-remitting MS,… read more

Celexa (Citalopram)

Overview
Celexa is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat depression. Celexa is sometimes prescribed to help treat depression associated with multiple sclerosis (MS). Celexa… read more

Complementary and alternative medicine (CAM) therapies

Overview
As many as 80 percent of people with multiple sclerosis (MS) choose to incorporate non-traditional therapies into their treatment plan. These treatments may be in addition to (complementary) or instead of… read more

Concerta (Methylphenidate)

Overview
Concerta is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat attention deficit hyperactivity disorder (ADHD) in people ages 6 to 65. Concerta is sometimes prescribed… read more

Copaxone (Glatiramer acetate)

Overview
Copaxone is a prescription medication approved by the Food and Drug Administration (FDA) for treating adults who have had their first episode of multiple sclerosis (MS) symptoms and whose magnetic resonance… read more

Cymbalta (Duloxetine)

Overview
Cymbalta is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat depression, anxiety, diabetic peripheral neuropathy, fibromyalgia, and chronic musculoskeletal pain. Cymbalta is… read more

Dalfampridine

Overview
Dalfampridine is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to improve walking speed in adults with relapsing multiple sclerosis (MS). It is the first drug approved for… read more

Diet

Overview
Like everyone else, people with multiple sclerosis (MS) feel their best when they consistently eat a healthy, balanced diet. Most physicians who specialize in MS recommend the same low-fat, high-fiber diet… read more

Effexor (Venlafaxine)

Overview
Effexor is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat major depressive disorder, generalized anxiety disorder, social anxiety disorder, and panic disorder. Effexor may… read more

Elavil (Amitriptyline)

Overview
Elavil is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat depression. Elavil may help manage neuropathic pain. Elavil is sometimes prescribed to treat depression and… read more

Exelon (Rivastigmine)

Overview
Exelon is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat mild to moderate dementia associated with Alzheimer’s disease. Exelon is sometimes prescribed off-label to treat… read more

Exercise

Overview
As recently as 20 years ago, doctors discouraged people with multiple sclerosis (MS) from being physically active. Exercise was deemed too dangerous. However, in recent years, many studies have proven that… read more

Extavia (Interferon beta 1b)

Overview
Extavia is a prescription medication approved by the Food and Drug Administration (FDA) for adults who have had their first episode of multiple sclerosis (MS) symptoms and whose magnetic resonance imaging (MRI)… read more

Gilenya (Fingolimod)

Overview
Gilenya is a prescription medication approved by the Food and Drug Administration (FDA) for treating relapsing forms of multiple sclerosis (MS) in adults. Gilenya is also known by its drug name, Fingolimod.… read more

Glatiramer acetate

Overview
Glatiramer acetate, sold under the brand name Copaxone, is a prescription medication approved by the Food and Drug Administration (FDA) for treating adults who have had one multiple sclerosis (MS) episode and… read more

Glatopa (Glatiramer acetate)

Overview
Glatopa is a prescription drug approved by the Food and Drug Administration (FDA) to treat people with relapsing forms of multiple sclerosis. Glatopa is also referred to by its drug name, Glatiramer acetate.… read more

Kesimpta (Ofatumumab)

Overview
Kesimpta is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat relapsing forms of multiple sclerosis in adults. Kesimpta is also referred to by its drug name, ofatumumab.… read more

Lemtrada (Alemtuzumab)

Overview
Lemtrada is a prescription medication approved by the Food and Drug Administration (FDA) for treating people 17 and older with relapsing forms of multiple sclerosis (MS). Lemtrada is also known by its drug… read more

Lexapro (Escitalopram)

Overview
Lexapro is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat major depressive disorder in adults and adolescents between the ages of 12 and 17. Lexapro is sometimes prescribed… read more

Lioresal (Baclofen)

The Lioresal brand name has been discontinued in the U.S. Generic alternatives may be available.

Overview
Lioresal is a prescription medication approved by the U.S. Food and Drug Administration (FDA) for treating…

Low-Dose Naltrexone

Overview
Naltrexone is a prescription medication approved by the U.S. Food and Drug Administration (FDA) for treating opiate and alcohol addiction. At a significantly lower dose, naltrexone has also been prescribed… read more

Lyrica (Pregabalin)

Overview
Lyrica is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat fibromyalgia, postherpetic neuralgia, partial onset seizures, and neuropathic pain associated with diabetic… read more

Mavenclad (Cladribine)

Overview
Mavenclad is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with relapsing forms of multiple sclerosis (MS) including relapsing-remitting MS and active… read more

Mayzent (Siponimod)

Overview
Mayzent is a prescription drug approved by the Food and Drug Administration (FDA) to treat adults with relapsing forms of multiple sclerosis (MS), including clinically isolated syndrome, relapsing-remitting MS,… read more

Natalizumab

Overview
Natalizumab, sold under the brand name Tysabri, is a prescription medication approved by the Food and Drug Administration (FDA) for treating adults with multiple sclerosis (MS). Natalizumab is not a cure for… read more

Neurontin (Gabapentin)

Overview
Neurontin is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat postherpetic neuralgia and some types of seizures. Neurontin is sometimes prescribed off-label to treat… read more

Novantrone (Mitoxantrone)

The Novantrone brand name has been discontinued in the U.S. Generic alternatives may be available.

Overview

Mitoxantrone is a prescription drug approved by the Food and Drug Administration (FDA) to reduce neurological…

Nuedexta (Dextromethorphan/Quinidine)

Overview
Nuedexta is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat pseudobulbar affect, or PBA (episodes of involuntary laughter or crying) in people with multiple sclerosis (MS)… read more

Occupational therapy

Overview
Occupational therapy is focused on maintaining and improving the ability to engage in daily activities, whether self-care, paid work or leisure pursuits. An occupational therapist can help people with multiple… read more

Ocrevus (Ocrelizumab)

Overview
Ocrevus is a prescription drug approved by the Food and Drug Administration (FDA) to treat both relapsing and primary progressive forms of multiple sclerosis. Ocrevus is also referred to by its drug name,… read more

Ocrevus Zunovo (Ocrelizumab and Hyaluronidase-Ocsq)

Overview
Ocrevus Zunovo is approved by the U.S. Food and Drug Administration (FDA) for treating relapsing forms of multiple sclerosis (MS), including clinically isolated syndrome, relapsing-remitting disease, and active…

Paxil (Paroxetine)

Overview
Paxil is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat depression, panic disorder, and obsessive-compulsive disorder. Paxil is sometimes prescribed to treat depression… read more

Physical therapy

Overview
From diagnosis of multiple sclerosis (MS) to advanced stages of the disease, physical therapy can help delay disability and preserve quality of life. A physical therapist will focus on your mobility issues and… read more

Plasma exchange

Overview
Plasma exchange, also known as plasmapheresis, is a short-term treatment for acute exacerbations in some people with relapsing forms of multiple sclerosis (MS). In 2011, the American Academy of Neurology (AAN)… read more

Plegridy (Peginterferon beta 1a)

Overview
Plegridy is a prescription medication approved by the Food and Drug Administration (FDA) in 2014 for people who have relapsing forms of multiple sclerosis (MS). The drug name of Plegridy is Peginterferon beta… read more

Ponvory (Ponesimod)

Overview
Ponvory is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat adults with relapsing forms of multiple sclerosis. Ponvory is also known by its drug name, ponesimod.

Ponvory… read more

Provigil (Modafinil)

Overview
Provigil is a prescription medication approved by the U.S. Food and Drug Administration (FDA) for the treatment of excessive sleepiness associated with narcolepsy, obstructive sleep apnea, and shift work… read more

Prozac (Fluoxetine)

Overview
Prozac is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat major depressive disorder, bulimia nervosa, panic disorder, and obsessive-compulsive disorder. Prozac is sometimes… read more

Rebif (Interferon beta 1a)

Overview
Rebif is a prescription medication approved by the Food and Drug Administration (FDA) for adults who have had their first episode of multiple sclerosis (MS) symptoms and whose magnetic resonance imaging (MRI)… read more

Ritalin LA (Methylphenidate Hydrochloride)

Overview
Ritalin LA is approved by the U.S. Food and Drug Administration (FDA) for the treatment of attention-deficit/hyperactivity disorder (ADHD) in children ages 6 to 12 years. It is sometimes prescribed off-label to…

Rituxan (Rituximab)

Overview
Rituxan is a prescription medication approved by the US Food and Drug Administration (FDA) in 1997. Rituxan is approved for the treatment of some types of lymphoma, leukemia, and arthritis. Although it is not… read more

Solu-Medrol (Methylprednisolone)

Overview
Solu-Medrol is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to reduce inflammation. Solu-Medrol is also known by its drug name, methylprednisolone. It is commonly… read more

Speech therapy

Overview
More than 40 percent of people with multiple sclerosis (MS) experience problems with speech at some point. Speech problems may take the form of dysarthria or dysphonia. Dysarthria, or speech disorder, could… read more

Symmetrel (Amantadine)

The Symmetrel brand name has been discontinued in the U.S. Generic alternatives may be available.

Overview

Symmetrel is a prescription medication approved by the U.S. Food and Drug Administration (FDA) for treating…

Tascenso ODT (Fingolimod)

Overview
Tascenso ODT is approved by the U.S. Food and Drug Administration (FDA) for treating relapsing forms of multiple sclerosis (MS), including clinically isolated syndrome (CIS), relapsing-remitting MS (RRMS), and…

Tecfidera (Dimethyl fumarate)

Overview
Tecfidera, also known by its drug name, Dimethyl fumarate, is a prescription medication approved by the Food and Drug Administration (FDA) for treating relapsing forms of multiple sclerosis (MS) in adults. Some… read more

Tyruko (Natalizumab-Sztn)

Overview

Tyruko is approved by the U.S. Food and Drug Administration (FDA) as a monotherapy for the treatment of relapsing forms of multiple sclerosis (MS), including clinically isolated syndrome, relapsing-remitting…

Tysabri (Natalizumab)

Overview
Tysabri is a prescription medication approved by the U.S. Food and Drug Administration (FDA) for treating adults with relapsing forms of multiple sclerosis (MS). Tysabri is also known by its drug name,… read more

Vitamin D

Overview
Vitamin D is a fat-soluble vitamin. This means that it is stored in fatty tissues until the body needs it. It is manufactured in the body from cholesterol when sunlight hits your skin.
Historically, doctors… read more

Vumerity (Diroximel fumarate)

Overview
Vumerity is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat relapsing forms of multiple sclerosis (MS) in adults, including clinically isolated syndrome,… read more

Wellbutrin (Bupropion)

Overview
Wellbutrin is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat depression in adults. Wellbutrin may help manage neuropathic pain. Wellbutrin is sometimes prescribed to treat… read more

Zanaflex (Tizanidine)

Overview
Zanaflex is a prescription medication approved by the U.S. Food and Drug Administration (FDA) for treating spasticity in adults with multiple sclerosis (MS). Zanaflex is not a cure for MS, but it can relieve… read more

Zeposia (Ozanimod)

Overview
Zeposia is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat relapsing forms of multiple sclerosis (MS) in adults, including clinically isolated syndrome,… read more

Zinbryta (Daclizumab)

On March 2, 2018, manufacturers Biogen and AbbVie announced that they were withdrawing Zinbryta (Daclizumab) from the market worldwide. The drug is no longer available.

For more details about this treatment, visit:… read more

Zoloft (Sertraline)

Overview
Zoloft is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat major depressive disorder in adults. Zoloft is sometimes prescribed to treat depression associated with multiple… read more