Connect with others who understand.

Sign up Log in
Resources
About MyMSTeam
Powered By
See answer
See answer
MULTIPLE SCLEROSIS
NEWS

Moderna Begins Testing Vaccine for Epstein-Barr — the Virus That May Be Behind MS

Medically reviewed by Amit M. Shelat, D.O.
Written by Torrey Kim
Posted on February 18, 2022
(Adobe Stock)


Biotechnology company Moderna Therapeutics has launched the first phase of a clinical trial to evaluate its vaccine for Epstein-Barr virus (EBV), dosing the first study participant on Jan. 5. Currently, no effective vaccine exists to prevent EBV, the virus that some scientists believe could trigger multiple sclerosis (MS).

EBV is a known cause of mononucleosis, a disease that’s common among teens. In addition, scientists believe that EBV may be “the leading cause of MS,” according to a study published in January, which analyzed data from more than 10 million members of the U.S. military. After reviewing 20 years’ worth of medical records, the researchers found a 32-fold higher MS risk following infection with EBV.

Moderna is in the early stages of its Eclipse Trial, which is evaluating outcomes of the vaccine in healthy people between the ages of 18 and 30 years of age. The vaccine uses messenger RNA (mRNA) technology, the same platform that Moderna uses in its COVID-19 vaccines.

Moderna is not the only company evaluating EBV vaccines, and inoculations against Epstein-Barr have been in development for years. Moderna’s technology aims to boost the immune system to prevent infection with EBV.

“In addition to using the mRNA platform, this vaccine differs from other EBV vaccines in development because it incorporates four glycoproteins expressed on the virus’ external surface that are used by the virus to enter cells,” said Dr. Katherine Luzuriaga, principal investigator for the study at UMass Chan Medical School, in a statement about the trial. “The goal is to raise robust immune responses to a broader range of proteins used by the virus for cell entry, in order to protect against infection and mononucleosis disease.”

Modern is still recruiting candidates to participate in the trial. More information is available here.

Amit M. Shelat, D.O. is a fellow of the American Academy of Neurology and the American College of Physicians. Review provided by VeriMed Healthcare Network. Learn more about him here.
Torrey Kim is a freelance writer with MyHealthTeam. Learn more about her here.

A MyMSTeam Member

Hurrah, for future people,

August 14, 2022
All updates must be accompanied by text or a picture.

We'd love to hear from you! Please share your name and email to post and read comments.

You'll also get the latest articles directly to your inbox.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service.
Privacy Policy
All updates must be accompanied by text or a picture.

Subscribe now to ask your question, get answers, and stay up to date on the latest articles.

Get updates directly to your inbox.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service.
Privacy Policy
MS News

Thank you for subscribing!

Become a member to get even more: