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MS and Mental Decline: 7 Strategies To Improve Memory and More

Medically reviewed by Amit M. Shelat, D.O.
Updated on January 18, 2023

Multiple sclerosis (MS) often causes cognitive symptoms such as problems with memory and executive function — the mental skills you use to control behaviors and get things done. Forgetting simple things and being unable to follow directions can make daily life a challenge. Additionally, MS may slow down your brain’s processing speed.

Cognitive problems occur in 40 percent to 65 percent of individuals with MS and typically cause impairments in attention, information processing speed, and memory. If you’re concerned about your cognitive abilities, talk to your doctor about cognitive testing.

If you’re experiencing memory loss, slowed thinking, or other issues with cognitive function, there are several strategies you can use to improve your functioning. Some are quick tips you can use today, while others may take time. Because MS is usually a lifelong condition, it’s good to think long term about ways to improve and preserve your cognitive abilities.

1. Try These Memory Tips

If you’re having problems with memory function, these tips may help:

  • Leave commonly used items in the same location (such as keys on a hook near the door).
  • Stick to daily routines.
  • Write down people’s names when you meet them.
  • Set reminders on your phone. If your smartphone has voice control, you may be able to simply tell it: “Set a reminder to call my doctor on Thursday at 2 p.m.”
  • Make to-do lists each day, and cross items off as you complete them.

2. Play Games To Improve Cognitive Reserve

“Cognitive reserve” refers to the brain’s ability to adapt, improvise, and be flexible. Keeping your brain stimulated and enriched can increase your cognitive reserve and help reduce the impact of MS-related changes in the brain.

Researchers have found that reading challenging materials can help improve skills in learning, memory, language, and problem-solving. There has also been interest in the use of video games to help people with MS. For instance, some researchers have focused on the use of the Nintendo Wii game system to help with multiple aspects of MS, including reducing falls.

Importantly, these video games have also been shown to help with cognition. One study found that ​​Dr Kawashima’s Brain Training from Nintendo improved executive functions such as information processing speed and cognitive fatigue. In this study, participants were required to play 30 minutes per day, five days a week, for eight consecutive weeks.

MyMSTeam members have discussed the best brain exercises to improve cognition and retain memory. One member asked if anyone had tried Luminosity, a brain-training program that uses web and mobile games to challenge core cognitive abilities. “I feel like my brain keeps skipping, and I’m looking for brain exercises that might help,” they wrote.

Another member replied that they used to use Luminosity often and that they had noticed it helped with brain fog. Other community members have found that Luminosity, card games, crosswords, and sudoku help improve their cognitive performance.

3. Stay Active With Regular Exercise

Regular exercise may also affect the cognitive changes that can come with MS. Physical activity can reverse some of the condition’s effects on the body. For example, MS leads to damage to the brain and nerve cells, but research shows that exercise helps neurons (brain cells) regenerate and reorganize.

Exercise can help brain health by increasing levels of a chemical known as brain-derived neurotrophic factor (BDNF). BDNF is helpful in learning and remembering. Studies support the idea of using exercise to raise BDNF levels.

In one study from the Journal of the Neurological Sciences, individuals with MS were found to have lower levels of BDNF in their blood compared to individuals without MS. After aerobic exercise, these BDNF levels increased.

Additionally, physical activity may help improve blood flow in the brain, reduce MS symptoms, change brain activity, and slow progression of the disease. When people with MS increase their fitness levels, they may also have better executive function and cognition.

However, some MyMSTeam members disagree on whether exercise reduces or increases their fatigue. One member warned against overdoing exercise to reap the cognitive benefits while avoiding negative effects like fatigue. “Gentle and steady does it!” they said.

4. Get Enough Sleep

Adults need between seven and nine hours of sleep every night, but many people with MS have trouble getting that much. Sleep disturbances negatively affect cognition and memory, as they’re very common among people with MS. As many as 60 percent of people living with MS have sleep problems, and more than 13,000 MyMSTeam members report insomnia as a symptom.

Try to prioritize getting a good night’s sleep and taking naps as needed. It’s best to stick to healthy sleep practices, and if you suspect you may have signs of a sleep disorder, seek diagnosis and treatment.

5. Do Your Hardest Thinking When You’re Sharpest

As much as possible, leave your most challenging cognitive tasks for when your brain function is at its peak. For instance, if you feel your sharpest in the morning, try to use that time to learn new information, make difficult decisions, or have complex conversations. If there’s a time when your brain is at its foggiest, try to avoid tackling tricky cognitive tasks during this period.

Keeping an MS symptom journal may help you pinpoint when your cognition will be at its worst. Rather than a time of day, some people find their brain fog is the worst based on when it’s time for their next MS treatment. “I feel I can tell when infusion time is near,” shared one member. “I think foggier and feel shaky.”

Some days are just off, and MyMSTeam members often recommend informing those around you and putting off anything that requires a great deal of thinking.

“Brain fog happens,” wrote one member. “When it strikes, I don’t sign anything, don’t drive, and I usually just make it a day where I either catch up on shows or crotchet ’cause I won’t trust myself. I have run my glasses through the dryer and dishwasher on days where things aren’t so clear.” Another added, “Some days are so bad I forget how to do basic things. I just let everyone know as well. Remember to be easy on yourself.”

6. Consider Cognitive Rehabilitation Therapy

Cognitive rehabilitation is another method for boosting cognitive abilities. Cognitive rehabilitation therapy is mental training that helps keep cognitive abilities sharp. If you have MS, training that improves cognitive function can significantly improve your life.

This training encompasses two types: restorative and compensatory. Restorative cognitive rehabilitation attempts to restore cognitive faculties that have been lost, while compensatory cognitive rehabilitation teaches strategies that compensate for cognitive impairment. Therapists generally use both types to help people with MS.

An example of restorative cognitive rehabilitation is when a person performs increasingly difficult memory tests to improve their memory or undergoes training to improve their attention span. An example of compensatory cognitive rehabilitation includes using calendars to help keep track of tasks and events.

Although there have been some difficulties in studying the effectiveness of cognitive rehabilitation therapy (mostly due to differences in study methods used), research seems to support that this type of therapy can improve attention, executive functions, and memory.

7. Look Into Cognitive Behavioral Therapy

Cognitive behavioral therapy (CBT) is a type of psychological treatment. It focuses on changing unhelpful thoughts and behaviors, improving emotional self-control, and developing coping strategies for stress and other challenges. CBT can help treat many conditions, including:

  • Depression
  • Anxiety disorders
  • Alcohol and drug use problems

Evidence from the Journal of Clinical Neuroscience suggests CBT can also help improve certain aspects of cognitive dysfunction.

People with MS commonly experience fatigue, which can affect their physical, mental, and social quality of life. However, studies have shown that CBT can help treat fatigue-related symptoms in people with MS. For example, CBT may be able to help improve attention in people with MS.

Building a Community

MyMSTeam is the social network for people with multiple sclerosis and their loved ones. On MyMSTeam, more than 195,000 members come together to ask questions, give advice, and share their stories with others who understand life with multiple sclerosis.

Have you found effective ways to manage memory problems or improve cognitive issues with MS? Share your experience in the comments below, or start a conversation by posting on your Activities page.

References
  1. Cognitive Impairment in Multiple Sclerosis — Minerva Medica
  2. Cognitive Health — National Multiple Sclerosis Society
  3. Influence of Formal Education on Cognitive Reserve in Patients With Multiple Sclerosis — Frontiers in Neurology
  4. The Use of Gaming Technology for Rehabilitation in People With Multiple Sclerosis — Multiple Sclerosis Journal
  5. A Low-Cost Cognitive Rehabilitation With a Commercial Video Game Improves Sustained Attention and Executive Functions in Multiple Sclerosis: A Pilot Study — Neurorehabilitation and Neural Repair
  6. Voluntary Exercise Induces a BDNF-Mediated Mechanism That Promotes Neuroplasticity — Journal of Neurophysiology
  7. Serum Brain-Derived Neurotrophic Factor Response to Aerobic Exercise in Multiple Sclerosis — Journal of the Neurological Sciences
  8. Hippocampal BDNF Mediates the Efficacy of Exercise on Synaptic Plasticity and Cognition — European Journal of Neuroscience
  9. Exercise and Disease Progression in Multiple Sclerosis: Can Exercise Slow Down the Progression of Multiple Sclerosis? — Therapeutic Advances in Neurological Disorders
  10. Improved Physical Fitness Correlates With Improved Cognition in Multiple Sclerosis — Archives of Physical Medicine and Rehabilitation
  11. How Much Sleep Do We Really Need? — Sleep Foundation
  12. Multiple Sclerosis Minute: Sleep and Multiple Sclerosis — Practical Neurology
  13. Sleep Disturbance and Memory Dysfunction in Early Multiple Sclerosis — Annals of Clinical & Translational Neurology
  14. Managing Cognitive Problems in MS — National Multiple Sclerosis Society
  15. Computer Assisted Retraining of Attentional Impairments in Patients With Multiple Sclerosis — Journal of Neurology, Neurosurgery and Psychiatry
  16. Treating Learning Impairments Improves Memory Performance in Multiple Sclerosis: A Randomized Clinical Trial — Multiple Sclerosis Journal
  17. Cognitive Behavioral Therapy — Mayo Clinic
  18. Cognitive Behavioral Therapies and Multiple Sclerosis Fatigue: A Review of Literature — Journal of Clinical Neuroscience
  19. Cognitive Behavioral Therapy Positively Affects Fatigue in Patients With Multiple Sclerosis: Results of a Randomized Controlled Trial — Multiple Sclerosis Journal
  20. Evidenced-Based Cognitive Rehabilitation for Persons With Multiple Sclerosis: A Review of the Literature — Archives of Physical Medicine and Rehabilitation
  21. Cognitive Rehabilitation for Multiple Sclerosis Patients With Executive Dysfunction — The Journal of Cognitive Rehabilitation
  22. Cognitive Reserve Moderates Decline in Information Processing Speed in Multiple Sclerosis Patients — Journal of the International Neuropsychological Society
Updated on January 18, 2023

A MyMSTeam Member

I definitely find I am sharpest I in the morning and will aim to schedule Important medical appointments at this time. Even taking my dog to the vet at first available appointment time. I asked the… read more

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Amit M. Shelat, D.O. is a fellow of the American Academy of Neurology and the American College of Physicians. Review provided by VeriMed Healthcare Network. Learn more about him here.
Brooke Dulka, Ph.D. is a freelance science writer and editor. She received her doctoral training in biological psychology at the University of Tennessee. Learn more about her here.
Kelly Crumrin is a senior editor at MyHealthTeam and leads the creation of content that educates and empowers people with chronic illnesses. Learn more about her here.

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